Altered expression of synaptic proteins and adhesion molecules in the hippocampus and cortex following the onset of diabetes in nonobese diabetic mice
Sign Up to like & getrecommendations! Published in 2023 at "Physiological Reports"
DOI: 10.14814/phy2.15673
Abstract: Mounting evidence links Type 1 diabetes (T1D) with cognitive dysfunction, psychiatric disorders, and synaptic alterations; however, the underlying mechanism remains unclear. Numerous synaptic proteins and synaptic adhesion molecules (SAMs) that orchestrate synaptic formation, restructuring, and… read more here.
Keywords: synaptic proteins; adhesion molecules; expression synaptic; mice ... See more keywords
Catalpol protects synaptic proteins from beta-amyloid induced neuron injury and improves cognitive functions in aged rats.
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DOI: 10.18632/oncotarget.17951
Abstract: Synapse loss is one of the common factors contributing to cognitive disorders, such as Alzheimer's disease (AD), which is manifested by the impairment of basic cognitive functions including memory processing, perception, problem solving, and language.… read more here.
Keywords: synaptic proteins; beta amyloid; cognitive functions; cognitive disorders ... See more keywords