Senescent human hematopoietic progenitors show elevated expression of transposable elements and inflammatory genes.
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DOI: 10.1016/j.exphem.2018.03.003
Abstract: Genomic transposable elements (TEs) constitute the majority of the genome. Expression of TEs is known to activate the double-stranded RNA recognition pathway ("viral mimicry"), leading to the activation of interferon-stimulated genes, inflammation, and immune-mediated cell… read more here.
Keywords: expression tes; senescence; human hematopoietic; inflammatory genes ... See more keywords