Articles with "expression top2a" as a keyword



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High expression of TOP2A gene predicted poor prognosis of hepatocellular carcinoma after radical hepatectomy

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Published in 2020 at "Translational cancer research"

DOI: 10.21037/tcr.2019.12.46

Abstract: Background: Topoisomerase (DNA) II alpha (TOP2A) is the up-regulated gene of the chromosome aggregation pathway. This gene encodes DNA topoisomerase, which can control and change the topological state of DNA during transcription and replication, participate… read more here.

Keywords: expression top2a; top2a expression; top2a; expression ... See more keywords

Nanoparticle-based hyperthermia distinctly impacts production of ROS, expression of Ki-67, TOP2A, and TPX2, and induction of apoptosis in pancreatic cancer

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Published in 2017 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s108577

Abstract: So far, the therapeutic outcome of hyperthermia has shown heterogeneous responses depending on how thermal stress is applied. We studied whether extrinsic heating (EH, hot air) and intrinsic heating (magnetic heating [MH] mediated by nanoparticles)… read more here.

Keywords: production; hyperthermia; expression top2a; pancreatic cancer ... See more keywords