How powerful are summary-based methods for identifying expression-trait associations under different genetic architectures?
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DOI: 10.1142/9789813235533_0021
Abstract: Transcriptome-wide association studies (TWAS) have recently been employed as an approach that can draw upon the advantages of genome-wide association studies (GWAS) and gene expression studies to identify genes associated with complex traits. Unlike standard… read more here.
Keywords: trait; trait associations; power; expression trait ... See more keywords