Multinational Analysis of Estimated Health Care Costs Related to Extended-Interval Fixed Dosing of Checkpoint Inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.0490
Abstract: Key Points Question Is extended-interval fixed dosing of pembrolizumab associated with increased health care costs? Findings This economic evaluation including simulated patients found that using the US Food and Drug Administration–labeled pembrolizumab dose of 400… read more here.
Keywords: health care; care costs; extended interval; interval fixed ... See more keywords
Efficacy and safety of natalizumab extended interval dosing.
Sign Up to like & getrecommendations! Published in 2018 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2018.06.015
Abstract: OBJECTIVE It is postulated that extending the dosing interval of natalizumab (NTZ) from 4 to 5-8 weeks might decrease the risk of progressive multifocal leukoencephalopathy (PML). The aim of this study was to assess the… read more here.
Keywords: sid eid; efficacy safety; safety natalizumab; extended interval ... See more keywords
Safety of Extended interval Dosing Immune Checkpoint Inhibitors: a multicentre cohort study.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the National Cancer Institute"
DOI: 10.1093/jnci/djad061
Abstract: BACKGROUND Real-life spectrum and survival implications of immune-related adverse events (irAEs) in patients treated with extended interval dosing (ED) immune checkpoint inhibitors (ICIs) are unknown. METHODS Characteristics of 812 consecutive solid cancer patients who received… read more here.
Keywords: checkpoint inhibitors; immune checkpoint; interval dosing; dosing immune ... See more keywords
Damage control surgery and extended interval GI reconstruction after trauma – a video vignette
Sign Up to like & getrecommendations! Published in 2017 at "Colorectal Disease"
DOI: 10.1111/codi.13651
Abstract: of a laparoscopic right colectomy with extracorporeal ileocolic anastomosis in an elderly lady with an obstructing caecal cancer and proximal SBO with markedly dilated small bowel loops. The authors show and explain the inherent difficulties… read more here.
Keywords: surgery extended; damage control; extended interval; reconstruction trauma ... See more keywords
A Pharmacokinetic Analysis of Tobramycin in Patients Less than Five Years of Age with Cystic Fibrosis: Assessment of Target Attainment with Extended-Interval Dosing through Simulation
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DOI: 10.1128/aac.02377-21
Abstract: Extended interval dosing of tobramycin is recommended for treatment of pulmonary exacerbations in adults and older children with cystic fibrosis (CF), but data are limited in patients less than 5 years of age. We performed a… read more here.
Keywords: tobramycin; interval dosing; years age; age ... See more keywords
Evaluation of SAMe-TT2R2 Score on Predicting Success With Extended-Interval Warfarin Monitoring
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DOI: 10.1177/1060028018779774
Abstract: Background: In patients with stable international normalized ratios, 12-week extended-interval warfarin monitoring can be considered; however, predictors of success with this strategy are unknown. The previously validated SAMe-TT2R2 score (considering sex, age, medical history, treatment,… read more here.
Keywords: tt2r2; tt2r2 score; interval warfarin; extended interval ... See more keywords
Ocrelizumab extended interval dosing in multiple sclerosis during SARS-CoV-2 pandemic: a real-world experience.
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DOI: 10.1177/13524585221123682
Abstract: BACKGROUND during COVID-19 pandemic, ocrelizumab administration was frequently postponed because of a lack of safety information and to favour vaccination. We assessed clinical implications of ocrelizumab administration delay in MS patients. METHODS we retrospectively classified… read more here.
Keywords: administration; interval dosing; ppms patients; cohort ... See more keywords