Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox
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DOI: 10.1002/cctc.201701379
Abstract: Chiral secondary and tertiary amines are ubiquitous in pharmaceutical, fine, and specialty chemicals, but their synthesis typically suffers from significant sustainability and selectivity challenges. Biocatalytic alternatives, such as enzyme‐catalyzed reductive amination, offer several advantages over… read more here.
Keywords: aminations extending; imine reductase; biocatalytic reductive; efficient biocatalytic ... See more keywords