Optimizing genome editing strategy by primer-extension-mediated sequencing
Sign Up to like & getrecommendations! Published in 2019 at "Cell Discovery"
DOI: 10.1038/s41421-019-0088-8
Abstract: Efficient and precise genome editing is essential for clinical applications and generating animal models, which requires engineered nucleases with high editing ability while low off-target activity. Here we present a high-throughput sequencing method, primer-extension-mediated sequencing… read more here.
Keywords: genome editing; mediated sequencing; extension mediated; target ... See more keywords