Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2215371120
Abstract: Significance Despite being identified as the strongest genetic risk factor for Alzheimer’s disease more than 20 years ago, a connection between the biochemical properties of apolipoprotein E (ApoE) and its role in the disease remains… read more here.
Keywords: lipid bound; apolipoprotein extensive; lipid; extensive conformational ... See more keywords