Effect of Extent of Supersaturation on the Evolution of Kinetic Solubility Profiles.
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DOI: 10.1021/acs.molpharmaceut.6b00788
Abstract: Solubility limited compounds require enabling formulations such as amorphous solid dispersions (ASDs) to increase the apparent solubility by dissolving to a concentration higher than the equilibrium solubility of the drug. This may lead to subsequent… read more here.
Keywords: kinetic solubility; extent supersaturation; solubility profiles; precipitation ... See more keywords