Mechanisms underlying the enhancement of γ‐aminobutyric acid responses in the external globus pallidus of R6/2 Huntington’s disease model mice
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24710
Abstract: In Huntington's disease (HD), the output of striatal indirect pathway medium‐sized spiny neurons (MSNs) is altered in its target region, the external globus pallidus (GPe). In a previous study we demonstrated that selective optogenetic stimulation… read more here.
Keywords: globus pallidus; external globus; huntington disease; mice ... See more keywords
Manganese exposure causes movement deficit and changes in the protein profile of the external globus pallidus in Sprague Dawley rats.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and industrial health"
DOI: 10.1177/07482337211022223
Abstract: Manganese (Mn) is required for normal brain development and function. Excess Mn may trigger a parkinsonian movement disorder but the underlying mechanisms are incompletely understood. We explored changes in the brain proteomic profile and movement… read more here.
Keywords: globus pallidus; movement; external globus; dawley rats ... See more keywords