Role of orexin-1 receptors in the dorsal hippocampus (CA1 region) in expression and extinction of the morphine-induced conditioned place preference in the rats
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DOI: 10.1016/j.peptides.2017.12.017
Abstract: HighlightsIntra‐CA1 administration of OX1r antagonist attenuated the expression of morphine‐induced CPP.Intra‐CA1 SB334867 reduced maintenance of morphine rewarding properties in the rats.Blockade of OX1 receptor in CA1 facilitated the extinction of morphine‐induced CPP. &NA; Orexinergic system… read more here.
Keywords: morphine induced; morphine; expression; cpp ... See more keywords
Molecular Mechanisms Underlying the Retrieval and Extinction of Morphine Withdrawal-Associated Memories in the Basolateral Amygdala and Dentate Gyrus
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DOI: 10.3390/biomedicines10030588
Abstract: Despite their indisputable efficacy for pain management, opiate prescriptions remain highly controversial partially due to their elevated addictive potential. Relapse in drug use is one of the principal problems for addiction treatment, with drug-associated memories… read more here.
Keywords: extinction morphine; retrieval extinction; extinction; morphine ... See more keywords