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Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5032-3
Abstract: RationaleOne approach to improving exposure therapy for anxiety disorders has focused on developing pharmacological adjuncts to enhance extinction, but these efforts have produced modest success in clinical trials. Understanding the factors that predict the efficacy…
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Keywords:
within session;
extinction recall;
extinction;
extinction training ... See more keywords
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Published in 2022 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2022.119080
Abstract: The cerebellum is involved in the acquisition and consolidation of learned fear responses. Knowledge about its contribution to extinction learning, however, is sparse. Extinction processes likely involve erasure of memories, but there is ample evidence…
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Keywords:
cerebellum;
extinction learning;
memory;
extinction training ... See more keywords
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Published in 2019 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2019.107088
Abstract: Female reproductive experience has been shown to alter the hormonal, neurobiological and behavioural features of fear extinction, which is the laboratory basis of exposure therapy. This raises uncertainties as to whether pharmacological agents that enhance…
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Keywords:
enhance fear;
extinction;
nulliparous primiparous;
extinction training ... See more keywords
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Published in 2018 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2018.05.003
Abstract: &NA; Converging crossâspecies evidence indicates that fear extinction (the laboratory basis of exposure therapy for anxiety disorders) in females is modulated by endogenous and exogenous estradiol. The mechanisms underlying estradiol's influences on fear extinction are…
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Keywords:
estradiol;
extinction;
extinction training;
activation ... See more keywords
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Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0223729
Abstract: Preclinical and clinical data have shown that D-cycloserine (DCS), a partial agonist at the N-methyl-d-aspartate receptor complex, augments the retention of fear extinction in animals and the therapeutic learning from exposure therapy in humans. However,…
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Keywords:
fear conditioning;
extinction;
extinction training;
fear extinction ... See more keywords