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Published in 2023 at "Human molecular genetics"
DOI: 10.1093/hmg/ddad056
Abstract: As an aneuploidy, trisomy is associated with mammalian embryonic and postnatal abnormalities. Understanding the underlying mechanisms involved in mutant phenotypes is broadly important and may lead to new strategies to treat clinical manifestations in individuals…
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Keywords:
gene dosage;
extra chromosome;
gene;
trisomy ... See more keywords
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Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2019.11035
Abstract: Translocation (9;11)(p21.3;q23.3) is one of the most common lysine methyltransferase 2A (KMT2A)-rearrangements in de novo and therapy-related acute myeloid leukemia (AML). Numerous in vitro and in vivo studies have demonstrated that the KMT2A/MLLT3 super elongation…
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Keywords:
derivative chromosome;
p21 q23;
case;
extra chromosome ... See more keywords