Extra-motor cerebral changes and manifestations in primary lateral sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Brain imaging and behavior"
DOI: 10.1007/s11682-020-00421-4
Abstract: Primary lateral sclerosis (PLS) is classically considered a 'pure' upper motor neuron disorder. Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of PLS, but extra-motor cerebral changes are poorly characterized. In… read more here.
Keywords: primary lateral; pls; motor cerebral; motor ... See more keywords
Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.750543
Abstract: Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) lie at opposing ends of a clinical, genetic, and neuropathological continuum. In the last decade, it has become clear that cognitive and behavioral changes in patients… read more here.
Keywords: pathophysiological underpinnings; motor neurodegeneration; motor; underpinnings extra ... See more keywords