Canonical and extra-telomeric functions of telomerase: Implications for healthy ageing conferred by endurance training.
Sign Up to like & getrecommendations! Published in 2023 at "Aging cell"
DOI: 10.1111/acel.13836
Abstract: Telomerase preserves genomic integrity by maintaining and protecting the telomeres. Seminal findings from 1985 revealed the canonical role of telomerase and motivated investigations into potential therapeutic strategies to combat one of the hallmarks of ageing-telomere… read more here.
Keywords: extra telomeric; telomerase; endurance training; canonical extra ... See more keywords
TERT Extra-Telomeric Roles: Antioxidant Activity and Mitochondrial Protection
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DOI: 10.3390/ijms24054450
Abstract: Telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase holoenzyme, which adds telomeric DNA repeats on chromosome ends to counteract telomere shortening. In addition, there is evidence of TERT non-canonical functions, among which is… read more here.
Keywords: extra telomeric; antioxidant activity; roles antioxidant; telomeric roles ... See more keywords