Expanding the search for significant EGFR mutations in NSCLC outside of the tyrosine kinase domain with next-generation sequencing
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DOI: 10.1007/s12032-017-0985-3
Abstract: While conventional organization of EGFR mutations in non-small cell lung cancer (NSCLC) includes classic lesions sensitive to tyrosine kinase inhibitors (TKI) and variants localized to the tyrosine kinase domain (TKD) in exons 18–21, next-generation sequencing… read more here.
Keywords: kinase domain; tyrosine kinase; egfr mutations; extra tkd ... See more keywords