Biomimetic Nanocarriers Guide Extracellular ATP Homeostasis to Remodel Energy Metabolism for Activating Innate and Adaptive Immunity System
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105376
Abstract: Metabolic interventions via targeting intratumoral dysregulated metabolism pathways have shown promise in reinvigorating antitumor immunity. However, approved small molecule immunomodulators often suffer from ineffective response rates and severe off‐target toxicity. ATP occupies a crucial role… read more here.
Keywords: metabolism; energy metabolism; immunity; tumor ... See more keywords
Molecular Mechanism of Plant Recognition of Extracellular ATP.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2017_110
Abstract: Adenosine 5'-triphosphate (ATP), a ubiquitously dispersed biomolecule, is not only a major source of biochemical energy for living cells, but also acts as a critical signaling molecule through inter-cellular communication. Recent studies have clearly shown… read more here.
Keywords: atp; plant recognition; extracellular atp; mechanism plant ... See more keywords
The real-time detection of acupuncture-induced extracellular ATP mobilization in acupoints and exploration of its role in acupuncture analgesia.
Sign Up to like & getrecommendations! Published in 2022 at "Purinergic signalling"
DOI: 10.1007/s11302-021-09833-3
Abstract: Our and in vitro studies had confirmed that mechanosensitive ATP release and accumulation in acupoints was elicited by acupuncture (AP), which might be a pivotal step for triggering AP analgesia. But to date, the dynamics… read more here.
Keywords: acupuncture; real time; eatp; extracellular atp ... See more keywords
ATP mediates a negative autocrine signal on stimulus-secretion coupling in mouse pancreatic β-cells
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1731-0
Abstract: PurposeThe role of ATP, which is secreted by pancreatic β-cells, is still a matter of debate. It has been postulated that extracellular ATP acts as a positive auto- or paracrine signal in β-cells amplifying insulin… read more here.
Keywords: secretion; atp; extracellular atp; signal ... See more keywords
Dangerously Fit: Extracellular ATP Aids Memory T Cell Metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "Immunity"
DOI: 10.1016/j.immuni.2018.08.009
Abstract: In a recent issue of Nature, Borges da Silva et al. (2018) reveal that P2RX7, a receptor for extracellular ATP, promotes CD8 T cell memory by enhancing metabolic fitness. This work links an ancient "danger" signal with… read more here.
Keywords: atp; extracellular atp; fit extracellular; cell ... See more keywords
Corrigendum to "Extracellular ATP and adenosine: The yin and yang in immune responses?" [Molecular Aspects of Medicine 55 (2017) 9-19].
Sign Up to like & getrecommendations! Published in 2017 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2017.08.003
Abstract: The authors regret that they did not mention this funding: This project has received funding from the Marie Curie International Research Staff Exchange Scheme with the 7th European Community Framework Program under grant agreement No.… read more here.
Keywords: medicine; molecular aspects; corrigendum extracellular; extracellular atp ... See more keywords
The Vesicular Transmitter Content in Chromaffin Cells can be Regulated via Extracellular ATP.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00494
Abstract: The energy carrying molecule adenosine triphosphate (ATP) has been implicated for its role in modulation of chemical signaling for some time. Despite this, the precise effects and mechanisms of action of ATP on secretory cells… read more here.
Keywords: vesicular transmitter; chromaffin cells; atp; extracellular atp ... See more keywords
Conversion of extracellular ATP into adenosine: a master switch in renal health and disease
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0304-7
Abstract: ATP and its ultimate degradation product adenosine are potent extracellular signalling molecules that elicit a variety of pathophysiological functions in the kidney through the activation of P2 and P1 purinergic receptors, respectively. Extracellular purines can… read more here.
Keywords: atp adenosine; extracellular atp; disease; kidney ... See more keywords
Advances in chilling injury of postharvest fruit and vegetable: Extracellular ATP aspects.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive reviews in food science and food safety"
DOI: 10.1111/1541-4337.13003
Abstract: Due to the global use of cold chain, the development of postharvest technology to reduce chilling injury (CI) in postharvest fruits and vegetables during storage and transport is needed urgently. Considerable evidence shows that maintaining… read more here.
Keywords: chilling injury; injury postharvest; postharvest fruits; fruits vegetables ... See more keywords
Pannexin‐1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration
Sign Up to like & getrecommendations! Published in 2019 at "Acta Physiologica"
DOI: 10.1111/apha.13360
Abstract: Extracellular ATP signalling is involved in many physiological and pathophysiological processes in several tissues, including adipose tissue. Adipocytes have crucial functions in lipid and glucose metabolism and they express purinergic receptors. However, the sources of… read more here.
Keywords: mediated atp; pannexin mediated; extracellular atp; release adipocytes ... See more keywords
Extracellular ATP promotes breast cancer invasion and epithelial‐mesenchymal transition via hypoxia‐inducible factor 2α signaling
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.14086
Abstract: Extracellular ATP has been shown to play an important role in invasion and the epithelial‐mesenchymal transition (EMT) process in breast cancer; however, the mechanism is unclear. Here, by using a cDNA microarray, we demonstrated that… read more here.
Keywords: hif; atp; invasion; extracellular atp ... See more keywords