Extracellular calcium regulates the adhesion and migration of osteoclasts via integrin αvβ 3/Rho A/Cytoskeleton signaling
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology International"
DOI: 10.1002/cbin.11033
Abstract: Integrin αvβ3 is a transmembrane integrin, which can initiate osteoclasts’ attachment on bones, leading to downward signaling pathways and subsequent bone resorption. Different calcium concentrations have been reported to have an influence on the activation… read more here.
Keywords: cytoskeleton; extracellular calcium; adhesion migration; integrin ... See more keywords
Signaling Pathways Linked to Serotonin-Induced Superoxide Anion Production: A Physiological Role for Mitochondria in Pulmonary Arteries
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2017.00076
Abstract: Serotonin (5-HT) is a potent vasoconstrictor agonist and contributes to several vascular diseases including systemic or pulmonary hypertension and atherosclerosis. Although superoxide anion (O2•_) is commonly associated to cellular damages due to O2•_ overproduction, we… read more here.
Keywords: signaling pathways; production; extracellular calcium; calcium ... See more keywords
Extracellular Calcium Influx Pathways in Astrocyte Calcium Microdomain Physiology
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DOI: 10.3390/biom11101467
Abstract: Astrocytes are complex glial cells that play many essential roles in the brain, including the fine-tuning of synaptic activity and blood flow. These roles are linked to fluctuations in intracellular Ca2+ within astrocytes. Recent advances… read more here.
Keywords: microdomain; extracellular calcium; physiology; ca2 ... See more keywords
Extracellular Calcium Receptor as a Target for Glutathione and Its Derivatives
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DOI: 10.3390/ijms23020717
Abstract: Extracellular glutathione (GSH) and oxidized glutathione (GSSG) can modulate the function of the extracellular calcium sensing receptor (CaSR). The CaSR has a binding pocket in the extracellular domain of CaSR large enough to bind either… read more here.
Keywords: gssg; glutathione; casr; receptor ... See more keywords
Extracellular Calcium-Induced Calcium Transient Regulating the Proliferation of Osteoblasts through Glycolysis Metabolism Pathways
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054991
Abstract: During bone remodeling, high extracellular calcium levels accumulated around the resorbing bone tissue as soon as the activation of osteoclasts. However, if and how calcium is involved in the regulation of bone remodeling remains unclear.… read more here.
Keywords: calcium; proliferation; high extracellular; calcium transient ... See more keywords