Artifactual hyperpolarization during extracellular electrical stimulation: Proposed mechanism of high-rate neuromodulation disproved
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DOI: 10.1016/j.brs.2017.12.004
Abstract: BACKGROUND Kilohertz-frequency electric field stimulation (kEFS) applied to the spinal cord can reduce chronic pain without causing the buzzing sensation (paresthesia) associated with activation of dorsal column fibers. This suggests that high-rate spinal cord stimulation… read more here.
Keywords: hyperpolarization; stimulation; patch clamp; extracellular electrical ... See more keywords