Cell surface heparan sulfate proteoglycans are involved in the extracellular Hsp90-stimulated migration and invasion of cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-018-0955-5
Abstract: The extracellular heat shock protein 90 (Hsp90) is known to participate in cell migration and invasion. Recently, we have shown that cell surface heparan sulfate proteoglycans (HSPGs) are involved in the binding and anchoring of… read more here.
Keywords: extracellular hsp90; hsp90; migration; cell ... See more keywords
Extracellular HSP90α Interacts With ER Stress to Promote Fibroblasts Activation Through PI3K/AKT Pathway in Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.708462
Abstract: Pulmonary fibrosis is characterized by alveolar epithelial cell injury, lung fibroblast proliferation, differentiation, and extracellular matrix (ECM) deposition. Our previous study indicated that extracellular HSP90α (eHSP90α) promotes pulmonary fibrosis by activating the MAPK signaling pathway.… read more here.
Keywords: extracellular hsp90; fibrosis; stress; pulmonary fibrosis ... See more keywords