Extracellular H+ Ions are a Novel Signal for Tyrosine Hydroxylase Activation in Catecholaminergic Cells.
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DOI: 10.1021/acschemneuro.2c00696
Abstract: Tyrosine hydroxylase catalyzes the rate-limiting step in the catecholamine biosynthetic pathway. Short-term TH activity is proposed to be regulated by the phosphorylation/dephosphorylation of regulatory domains Ser 40, 31, and/or 19 in response to membrane depolarization… read more here.
Keywords: tyrosine hydroxylase; novel signal; mediated activation; extracellular ions ... See more keywords