A Light‐Curable and Tunable Extracellular Matrix Hydrogel for In Situ Suture‐Free Corneal Repair
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DOI: 10.1002/adfm.202113383
Abstract: Corneal injuries are a major cause of blindness worldwide. To restore corneal integrity and clarity, there is a need for regenerative biointegrating materials for in situ repair and replacement of corneal tissue. Here, light‐curable cornea… read more here.
Keywords: extracellular matrix; hydrogel; light curable; corneal ... See more keywords
High‐Throughput Screening of Vascular Endothelium‐Destructive or Protective Microenvironments: Cooperative Actions of Extracellular Matrix Composition, Stiffness, and Structure
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DOI: 10.1002/adhm.201601426
Abstract: Pathological modification of the subendothelial extracellular matrix (ECM) has closely been associated with endothelial activation and subsequent cardiovascular disease progression. To understand regulatory mechanisms of these matrix modifications, the majority of previous efforts have focused… read more here.
Keywords: endothelium; extracellular matrix; stiffness structure; composition ... See more keywords
Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing
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DOI: 10.1002/adhm.201701175
Abstract: Historically, soy protein and extracts have been used extensively in foods due to their high protein and mineral content. More recently, soy protein has received attention for a variety of its potential health benefits, including… read more here.
Keywords: protein; wound healing; sph; extracellular matrix ... See more keywords
A Bioprinted Cardiac Patch Composed of Cardiac‐Specific Extracellular Matrix and Progenitor Cells for Heart Repair
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DOI: 10.1002/adhm.201800672
Abstract: Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy has increased survival. Despite improved outcomes, many children develop reduced cardiac function and heart failure requiring transplantation. Human cardiac progenitor cell… read more here.
Keywords: heart; extracellular matrix; progenitor; cecm ... See more keywords
Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering.
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DOI: 10.1002/adhm.201801578
Abstract: The extracellular matrix (ECM) is a complex and dynamic structural scaffold for cells within tissues and plays an important role in regulating cell function. Recently it has become appreciated that the ECM contains bioactive motifs… read more here.
Keywords: engineering; immunomodulatory biomaterials; matrix based; extracellular matrix ... See more keywords
A Hydrogen-Bonded Extracellular Matrix-Mimicking Bactericidal Hydrogel with Radical Scavenging and Hemostatic Function for pH-Responsive Wound Healing Acceleration.
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DOI: 10.1002/adhm.202001122
Abstract: Generation of reactive oxygen species, delayed blood clotting, prolonged inflammation, bacterial infection, and slow cell proliferation are the main challenges of effective wound repair. Herein, a multifunctional extracellular matrix-mimicking hydrogel is fabricated through abundant hydrogen… read more here.
Keywords: hydrogen bonded; hydrogel; extracellular matrix; matrix ... See more keywords
Nanomedicine Strategies to Circumvent Intratumor Extracellular Matrix Barriers for Cancer Therapy.
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DOI: 10.1002/adhm.202101428
Abstract: The dense and heterogeneous physical network of the extracellular matrix (ECM) in tumors represents a formidable barrier that limits intratumor drug delivery and the therapeutic efficacy of many anticancer therapies. In this review, we summarize… read more here.
Keywords: extracellular matrix; intratumor extracellular; nanomedicine strategies; circumvent intratumor ... See more keywords
An Extracellular Matrix-liposome Composite, a Novel Extracellular Matrix Delivery System for Accelerated Tissue Regeneration.
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DOI: 10.1002/adhm.202101599
Abstract: xxxx. This article is protected by copyright. All rights reserved. read more here.
Keywords: novel extracellular; extracellular matrix; matrix; liposome composite ... See more keywords
A Bioprinted Tubular Intestine Model using a Colon-Specific Extracellular Matrix Bioink.
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DOI: 10.1002/adhm.202101768
Abstract: Tremendous advances have been made toward accurate recapitulation of the human intestinal system in vitro to understand its developmental process, and disease progression. However, current in vitro models are often confined to 2D or 2.5D… read more here.
Keywords: extracellular matrix; tissue; colon; model ... See more keywords
Injectable Extracellular Matrix Microparticles Promote Heart Regeneration in Mice with Post-ischemic Heart Injury.
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DOI: 10.1002/adhm.202102265
Abstract: XXXX This article is protected by copyright. All rights reserved. read more here.
Keywords: microparticles promote; promote heart; injectable extracellular; extracellular matrix ... See more keywords
Lipoplex‐Functionalized Thin‐Film Surface Coating Based on Extracellular Matrix Components as Local Gene Delivery System to Control Osteogenic Stem Cell Differentiation
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DOI: 10.1002/adhm.202201978
Abstract: A gene‐activated surface coating is presented as a strategy to design smart biomaterials for bone tissue engineering. The thin‐film coating is based on polyelectrolyte multilayers composed of collagen I and chondroitin sulfate, two main biopolymers… read more here.
Keywords: gene; extracellular matrix; thin film; surface ... See more keywords