Therapeutic use of extracellular mitochondria in CNS injury and disease
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.113114
Abstract: In the central nervous system (CNS), neuronal functionality is highly dependent on mitochondrial integrity and activity. In the context of a damaged or diseased brain, mitochondrial dysfunction leads to reductions in ATP levels, thus impairing… read more here.
Keywords: use extracellular; therapeutic use; mitochondria cns; cns injury ... See more keywords
Alternative mitochondrial quality control mediated by extracellular release
Sign Up to like & getrecommendations! Published in 2020 at "Autophagy"
DOI: 10.1080/15548627.2020.1848130
Abstract: ABSTRACT Mitochondrial quality control, which is crucial for maintaining cellular homeostasis, has been considered to be achieved exclusively through mitophagy. Here we report an alternative mitochondrial quality control pathway mediated by extracellular mitochondria release. By… read more here.
Keywords: protein; control; extracellular mitochondria; mitochondrial quality ... See more keywords
Extracellular Mitochondria and Vesicles.
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/circresaha.119.315328
Abstract: Monocyte interaction with endothelial cells is regarded as a key step in acute and chronic vascular inflammatory diseases. For many years, unraveling cell secretome composition has been an area of extensive investigation to better understand… read more here.
Keywords: extracellular mitochondria; mitochondria vesicles; extracellular vesicles;