Effects of Extracellular Potassium on Calcium Handling and Force Generation in a Model of Excitation-Contraction Coupling in Skeletal Muscle.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2021.110656
Abstract: It is well-established that extracellular potassium (Ko+) accumulation reduces muscle fiber excitability, however the effects of Ko+ on the excitation-contraction coupling (ECC) pathway are less understood. In vivo and in vitro studies following fatiguing stimulation… read more here.
Keywords: contraction coupling; model; extracellular potassium; force ... See more keywords
Effects of dose rate absorption in extracellular potassium concentration of red cells concentrates
Sign Up to like & getrecommendations! Published in 2020 at "Radiation Physics and Chemistry"
DOI: 10.1016/j.radphyschem.2019.05.032
Abstract: Abstract Blood irradiation is an essential practice to prevent transfusion-associated graft versus host disease (TA-GVHD), a rare and fatal syndrome. In this procedure, the T lymphocytes are inactivated; otherwise, after transfused to immunodepressed patients, they… read more here.
Keywords: dose rate; blood; potassium concentration; extracellular potassium ... See more keywords
Contributions of Astrocyte and Neuronal Volume to CA1 Neuron Excitability Changes in Elevated Extracellular Potassium
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.930384
Abstract: Rapid increases in cell volume reduce the size of the extracellular space (ECS) and are associated with elevated brain tissue excitability. We recently demonstrated that astrocytes, but not neurons, rapidly swell in elevated extracellular potassium… read more here.
Keywords: neuronal excitability; elevated extracellular; extracellular potassium; volume ... See more keywords
Sensitivity to extracellular potassium underlies type-intrinsic differences in retinal ganglion cell excitability
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DOI: 10.3389/fncel.2022.966425
Abstract: Neuronal type-specific physiologic heterogeneity can be driven by both extrinsic and intrinsic mechanisms. In retinal ganglion cells (RGCs), which carry visual information from the retina to central targets, evidence suggests intrinsic properties shaping action potential… read more here.
Keywords: potassium; sensitivity extracellular; extracellular potassium; excitability ... See more keywords
Effects of Increased Extracellular Potassium Concentration Induced by Ischemia on the Vulnerability of Ventricular Arrhythmias and the Regularity of Related Ventricular Tachycardia
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DOI: 10.3390/app11052189
Abstract: Myocardial ischemia could induce arrhythmias such as ventricular tachycardia and ventricular fibrillation, leading to sudden death and other serious consequences. This manuscript adopted the cardiac modeling and simulation method to study the activity pattern of… read more here.
Keywords: ventricular tachycardia; potassium concentration; extracellular potassium; vulnerability ... See more keywords