Enhancing extracellular protein production in Escherichia coli by deleting the d‐alanyl‐d‐alanine carboxypeptidase gene dacC
Sign Up to like & getrecommendations! Published in 2019 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201800199
Abstract: d‐Alanyl‐d‐alanine carboxypeptidase DacC is important for synthesis and stabilization of the peptidoglycan layer of Escherichia coli. In this work, dacC of E. coli BL21 (DE3) was successfully deleted, and the effects of this deletion on… read more here.
Keywords: production; extracellular protein; dacc; coli ... See more keywords
The ABC transporter Snu and the extracellular protein Snsl cooperate in the formation of the lipid-based inward and outward barrier in the skin of Drosophila.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2017.12.003
Abstract: Lipids in extracellular matrices (ECM) contribute to barrier function and stability of epithelial tissues such as the pulmonary alveoli and the skin. In insects, skin waterproofness depends on the outermost layer of the extracellular cuticle… read more here.
Keywords: barrier; abc transporter; snu extracellular; extracellular protein ... See more keywords
Effect of pH values on extracellular protein and polysaccharide secretions of Acidithiobacillus ferrooxidans during chalcopyrite bioleaching
Sign Up to like & getrecommendations! Published in 2017 at "Transactions of Nonferrous Metals Society of China"
DOI: 10.1016/s1003-6326(17)60046-3
Abstract: Abstract The effect of pH values on the extracellular protein and polysaccharide secretions of Acidithiobacillus ferrooxidans was comparatively investigated in different phases of bacterial growth during chalcopyrite bioleaching. The results indicate that the extracellular protein… read more here.
Keywords: protein polysaccharide; values extracellular; extracellular protein; polysaccharide secretions ... See more keywords
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
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DOI: 10.1038/nm.4256
Abstract: Mammalian tissues rely on a variety of nutrients to support their physiological functions. It is known that altered metabolism is involved in the pathogenesis of cancer, but which nutrients support the inappropriate growth of intact… read more here.
Keywords: catabolism; pancreatic tumors; extracellular protein; cancer cells ... See more keywords
Extracellular protein degradation via the lysosome
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DOI: 10.1038/s42004-020-00397-8
Abstract: Tight regulation of protein levels is so crucial for cellular function that mammalian cells have evolved two parallel degradation systems. This article discusses how these systems can be exploited to selectively target proteins of interest… read more here.
Keywords: protein; degradation; via lysosome; extracellular protein ... See more keywords
Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Immunology Research"
DOI: 10.1155/2017/2197615
Abstract: Pathogens have evolved unique mechanisms to breach the cell surface barrier and manipulate the host immune response to establish a productive infection. Proteins exposed to the extracellular environment, both cell surface-expressed receptors and secreted proteins,… read more here.
Keywords: pathogen; protein interactions; extracellular protein; extracellular host ... See more keywords
Pancreatic Tumors Exhibit Enhanced Extracellular Protein Catabolism.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2017-010
Abstract: PDACs gain necessary amino acids via macropinocytosis and degradation of extracellular proteins. read more here.
Keywords: pancreatic tumors; enhanced extracellular; tumors exhibit; extracellular protein ... See more keywords
High-Content Imaging for Large-Scale Detection of Low-Affinity Extracellular Protein Interactions
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DOI: 10.1177/2472555219879053
Abstract: Extracellular protein interactions coordinate cellular responses with their local environment and have important roles in pathogen invasion and disease. Due to technical challenges associated with studying binding events at the cell surface, the systematic and… read more here.
Keywords: large scale; high content; protein interactions; extracellular protein ... See more keywords
Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Neurodegeneration"
DOI: 10.1186/s13024-021-00465-0
Abstract: Alzheimer’s disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ) peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary tangles. Extensive research has focused on understanding the assembly mechanisms… read more here.
Keywords: alzheimer disease; extracellular protein; disease; pathology ... See more keywords
Accelerated directed evolution of dye-decolorizing peroxidase using a bacterial extracellular protein secretion system (BENNY)
Sign Up to like & getrecommendations! Published in 2019 at "Bioresources and Bioprocessing"
DOI: 10.1186/s40643-019-0255-7
Abstract: BackgroundDye-decolorizing peroxidases (DyPs) are haem-containing peroxidases that show great promises in industrial biocatalysis and lignocellulosic degradation. Through the use of Escherichia coli osmotically-inducible protein Y (OsmY) as a bacterial extracellular protein secretion system (BENNY), we… read more here.
Keywords: protein; secretion; extracellular protein; bacterial extracellular ... See more keywords