Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response
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DOI: 10.1126/sciadv.aba3688
Abstract: Metabolic analysis of ADA2-deficient cells shows that extracellular purine nucleosides trigger cellular innate immunity. Mechanisms linking immune sensing of DNA danger signals in the extracellular environment to innate pathways in the cytosol are poorly understood.… read more here.
Keywords: purine nucleosides; ifn response; dino; extracellular purine ... See more keywords