Activation of P2X4 receptors induces an increase in the area of the extracellular region and a decrease in receptor mobility
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13942
Abstract: The P2X4 receptor (P2X4R) is an ATP‐gated cation channel. Here, we used fast‐scan atomic force microscopy (AFM) to visualize changes in the structure and mobility of individual P2X4Rs in response to activation. P2X4Rs were purified… read more here.
Keywords: extracellular region; mobility; activation; area extracellular ... See more keywords
Extracellular region of epidermal growth factor receptor: a potential target for anti-EGFR drug discovery
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DOI: 10.1038/onc.2016.393
Abstract: The epidermal growth factor receptor (EGFR) is a transmembrane receptor with tyrosine kinase activity involved in regulation of cellular multiplication, survival, differentiation and metastasis. Our knowledge about function and complex management of these receptors has… read more here.
Keywords: extracellular region; factor receptor; growth factor; anti egfr ... See more keywords