Extracellular Spermine Activates DNA Methyltransferase 3A and 3B
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DOI: 10.3390/ijms20051254
Abstract: We first demonstrated that long-term increased polyamine (spermine, spermidine, putrescine) intake elevated blood spermine levels in mice and humans, and lifelong consumption of polyamine-rich chow inhibited aging-associated increase in aberrant DNA methylation, inhibited aging-associated pathological… read more here.
Keywords: spermine; methylation; extracellular spermine; aging associated ... See more keywords