Extracellular Trap-Mimicking DNA-Histone Mesostructures Synergistically Activate Dendritic Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900926
Abstract: Extracellular traps (ETs), such as neutrophil extracellular traps, are a physical mesh deployed by immune cells to entrap and constrain pathogens. ETs are immunogenic structures composed of DNA, histones, and an array of variable protein… read more here.
Keywords: extracellular trap; dna; dna histone; dendritic cells ... See more keywords
MUC5B induces in vitro neutrophil extracellular trap formation: Implication in otitis media
Sign Up to like & getrecommendations! Published in 2020 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.396
Abstract: Chronic otitis media (COM) is characterized by middle ear fluid predominantly containing cytokines, Nontypeable haemophilus influenzae (NTHi), the mucin MUC5B, and neutrophil extracellular traps (NETs). NETs consist of extracellular DNA coated with antibacterial proteins such… read more here.
Keywords: muc5b induces; neutrophil extracellular; otitis media; extracellular trap ... See more keywords
Validation of CDr15 as a new dye for detecting neutrophil extracellular trap.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.153
Abstract: Neutrophil extracellular trap (NET) is one of the first-line defenses against microbes. Under certain circumstances, however, it also plays an aggravating factor in diverse inflammation-related diseases including cancers and vascular diseases. Our aim is to… read more here.
Keywords: neutrophil extracellular; extracellular trap; net; validation cdr15 ... See more keywords
Extracellular trap‐like fiber release may not be a prominent defence response in snails: evidence from three species of freshwater gastropod molluscs
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.10.011
Abstract: ABSTRACT The discovery that mammalian neutrophils generate extracellular chromatin fibers that entrap/kill bacteria supported a new paradigm for innate immunity in animals. Similar findings in other models across diverse taxa have led to the hypothesis… read more here.
Keywords: like fibers; trap like; like fiber; extracellular trap ... See more keywords
1,25-Dihydroxyvitamin D3 induces formation of neutrophil extracellular trap-like structures and modulates the transcription of genes whose products are neutrophil extracellular trap-associated proteins: A pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Steroids"
DOI: 10.1016/j.steroids.2018.11.001
Abstract: &NA; Neutrophils are components of the innate immune system that participate in controlling infectious diseases through microbicidal mechanisms such as phagocytosis, degranulation and the release of neutrophil extracellular traps (NETs). NETs are DNA structures that… read more here.
Keywords: neutrophil extracellular; extracellular trap; transcription genes; whose products ... See more keywords
Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15668-z
Abstract: Because neutrophil extracellular trap (NET) formation is involved in the pathology of a wide variety of diseases, NET-regulating compounds are expected to be useful for the therapies of these diseases. In this study, we identified… read more here.
Keywords: neutrophil extracellular; extracellular trap; ether linked; hyperoxidation ether ... See more keywords
Extracellular trap can be trained as a memory response
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2046950
Abstract: ABSTRACT Extracellular trap (ET) appears as a double-edged sword for the host since it participates in host immune defense by entrapping pathogens, while excessive ET release also contributes to various diseases progression including atherosclerosis, cancer,… read more here.
Keywords: memory; memory response; extracellular trap; trained memory ... See more keywords
Evaluation of neutrophil extracellular trap deregulated formation in pyoderma gangrenosum
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Dermatology"
DOI: 10.1111/exd.14397
Abstract: Pyoderma gangrenosum (PG) is a neutrophilic dermatose (ND) characterized by a dense neutrophilic infiltrate in the affected tissue. Neutrophil extracellular traps (NETs) are web‐like structures released by neutrophils and composed of cytosolic and granule proteins… read more here.
Keywords: neutrophil extracellular; extracellular trap; netosis; pyoderma gangrenosum ... See more keywords
Increased Dietary Manganese Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00685-21
Abstract: Dietary metals can modify the risk to infection. Previously, we demonstrated that heightened dietary manganese (Mn) during systemic Staphylococcus aureus infection increases S. aureus virulence. ABSTRACT Dietary metals can modify the risk to infection. Previously,… read more here.
Keywords: dietary manganese; extracellular trap; infection; neutrophil extracellular ... See more keywords
Increased Neutrophil Extracellular Trap Formation in Uremia Is Associated with Chronic Inflammation and Prevalent Coronary Artery Disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Immunology Research"
DOI: 10.1155/2017/8415179
Abstract: Background. Neutrophils are involved in the pathogenesis of atherosclerosis by neutrophil extracellular trap (NET) formation. We hypothesized that the NET formation of neutrophils might be changed in end-stage renal disease (ESRD) patients, explaining their higher… read more here.
Keywords: uremia associated; neutrophil extracellular; extracellular trap; coronary artery ... See more keywords
Molecular Prerequisites for Neutrophil Extracellular Trap Formation and Evasion Mechanisms of Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.836278
Abstract: NETosis is a multi-facetted cellular process that promotes the formation of neutrophil extracellular traps (NETs). NETs as web-like structures consist of DNA fibers armed with granular proteins, histones, and microbicidal peptides, thereby exhibiting pathogen-immobilizing and… read more here.
Keywords: extracellular trap; molecular prerequisites; neutrophil extracellular; staphylococcus aureus ... See more keywords