Extracellular Trap-Mimicking DNA-Histone Mesostructures Synergistically Activate Dendritic Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900926
Abstract: Extracellular traps (ETs), such as neutrophil extracellular traps, are a physical mesh deployed by immune cells to entrap and constrain pathogens. ETs are immunogenic structures composed of DNA, histones, and an array of variable protein… read more here.
Keywords: extracellular trap; dna; dna histone; dendritic cells ... See more keywords
Functional 2D Nanoplatforms Alleviate Eosinophilic Chronic Rhinosinusitis by Modulating Eosinophil Extracellular Trap Formation
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DOI: 10.1002/advs.202307800
Abstract: The therapeutic outcomes of patients with eosinophilic chronic rhinosinusitis (ECRS) remain unsatisfactory, largely because the underlying mechanisms of eosinophilic inflammation are uncertain. Here, it is shown that the nasal secretions of ECRS patients have high… read more here.
Keywords: chronic rhinosinusitis; eosinophil extracellular; eosinophilic chronic; extracellular trap ... See more keywords
MUC5B induces in vitro neutrophil extracellular trap formation: Implication in otitis media
Sign Up to like & getrecommendations! Published in 2020 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.396
Abstract: Chronic otitis media (COM) is characterized by middle ear fluid predominantly containing cytokines, Nontypeable haemophilus influenzae (NTHi), the mucin MUC5B, and neutrophil extracellular traps (NETs). NETs consist of extracellular DNA coated with antibacterial proteins such… read more here.
Keywords: muc5b induces; neutrophil extracellular; otitis media; extracellular trap ... See more keywords
Validation of CDr15 as a new dye for detecting neutrophil extracellular trap.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.153
Abstract: Neutrophil extracellular trap (NET) is one of the first-line defenses against microbes. Under certain circumstances, however, it also plays an aggravating factor in diverse inflammation-related diseases including cancers and vascular diseases. Our aim is to… read more here.
Keywords: neutrophil extracellular; extracellular trap; net; validation cdr15 ... See more keywords
Extracellular trap‐like fiber release may not be a prominent defence response in snails: evidence from three species of freshwater gastropod molluscs
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.10.011
Abstract: ABSTRACT The discovery that mammalian neutrophils generate extracellular chromatin fibers that entrap/kill bacteria supported a new paradigm for innate immunity in animals. Similar findings in other models across diverse taxa have led to the hypothesis… read more here.
Keywords: like fibers; trap like; like fiber; extracellular trap ... See more keywords
1,25-Dihydroxyvitamin D3 induces formation of neutrophil extracellular trap-like structures and modulates the transcription of genes whose products are neutrophil extracellular trap-associated proteins: A pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Steroids"
DOI: 10.1016/j.steroids.2018.11.001
Abstract: &NA; Neutrophils are components of the innate immune system that participate in controlling infectious diseases through microbicidal mechanisms such as phagocytosis, degranulation and the release of neutrophil extracellular traps (NETs). NETs are DNA structures that… read more here.
Keywords: neutrophil extracellular; extracellular trap; transcription genes; whose products ... See more keywords
Modulating Neutrophil Extracellular Trap Formation In Vivo with Locoregional Precision Using Differently Charged Self-Assembled Hydrogels
Sign Up to like & getrecommendations! Published in 2024 at "ACS Central Science"
DOI: 10.1021/acscentsci.4c02198
Abstract: Neutrophil extracellular traps (NETs) are DNA networks released by neutrophils first described as a defense response against pathogens but have since been associated with numerous inflammatory diseases. The ability to induce NETs with locoregional specificity… read more here.
Keywords: neutrophil extracellular; modulating neutrophil; self assembled; extracellular trap ... See more keywords
Recognition and control of neutrophil extracellular trap formation by MICL
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DOI: 10.1038/s41586-024-07820-3
Abstract: Regulation of neutrophil activation is critical for disease control. Neutrophil extracellular traps (NETs), which are web-like structures composed of DNA and neutrophil-derived proteins, are formed following pro-inflammatory signals; however, if this process is uncontrolled, NETs… read more here.
Keywords: neutrophil extracellular; control neutrophil; trap formation; formation micl ... See more keywords
Mouse Bone Marrow Neutrophil Extracellular Trap Proteomics by Microbial Stimuli
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DOI: 10.1038/s41597-025-05181-8
Abstract: Neutrophils, the most abundant white blood cells in human circulation, play a crucial role in innate immunity. One of their key defense mechanisms is the formation of neutrophil extracellular traps (NETs), web-like structures composed of… read more here.
Keywords: neutrophil extracellular; trap proteomics; marrow neutrophil; extracellular trap ... See more keywords
Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation
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DOI: 10.1038/s41598-017-15668-z
Abstract: Because neutrophil extracellular trap (NET) formation is involved in the pathology of a wide variety of diseases, NET-regulating compounds are expected to be useful for the therapies of these diseases. In this study, we identified… read more here.
Keywords: neutrophil extracellular; extracellular trap; ether linked; hyperoxidation ether ... See more keywords
A neutrophil extracellular trap-related risk score predicts prognosis and characterizes the tumor microenvironment in multiple myeloma
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DOI: 10.1038/s41598-024-52922-7
Abstract: Multiple myeloma (MM) is a distinguished hematologic malignancy, with existing studies elucidating its interaction with neutrophil extracellular traps (NETs), which may potentially facilitate tumor growth. However, systematic investigations into the role of NETs in MM… read more here.
Keywords: neutrophil extracellular; multiple myeloma; risk; extracellular trap ... See more keywords