Serum small extracellular vesicle‐derived LINC00853 as a novel diagnostic marker for early hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12745
Abstract: This study aimed to identify novel long noncoding RNA (lncRNA) biomarkers for hepatocellular carcinoma (HCC) using publicly available tissue genomic datasets and validate their diagnostic utility for early‐stage HCC. Differentially expressed lncRNAs between 371 HCC… read more here.
Keywords: hepatocellular carcinoma; extracellular vesicle; hcc; derived linc00853 ... See more keywords
Quantitative and Multiplex Detection of Extracellular Vesicle‐Derived MicroRNA via Rolling Circle Amplification within Encoded Hydrogel Microparticles
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102332
Abstract: Extracellular vesicle‐derived microRNA (EV‐miRNA) represent a promising cancer biomarker for disease diagnosis and monitoring. However, existing techniques to detect EV‐miRNA rely on complex, bias‐prone strategies, and preprocessing steps, making absolute quantification highly challenging. This work… read more here.
Keywords: extracellular vesicle; derived microrna; detection; vesicle derived ... See more keywords
Extracellular Vesicle Mimetics: Preparation from Top‐Down Approaches and Biological Functions
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200142
Abstract: Extracellular vesicles (EVs) have attracted attention as delivery vehicles due to their structure, composition, and unique properties in regeneration and immunomodulation. However, difficulties during production and isolation processes of EVs limit their large‐scale clinical applications.… read more here.
Keywords: vesicle mimetics; preparation top; mimetics preparation; extracellular vesicle ... See more keywords
Photoactivatable Silencing Extracellular Vesicle (PASEV) Sensitizes Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202204765
Abstract: Immunotherapy has delivered impressive outcomes in combating tumor malignancies. However, insufficient immune infiltration and poor immunogenicity within the tumor microenvironment (TME) greatly compromise patient response rates. Here, a photoactivatable silencing extracellular vesicle (PASEV) is developed… read more here.
Keywords: immunotherapy; extracellular vesicle; photoactivatable silencing; silencing extracellular ... See more keywords
MIFlowCyt‐EV: The Next Chapter in the Reporting and Reliability of Single Extracellular Vesicle Flow Cytometry Experiments
Sign Up to like & getrecommendations! Published in 2020 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24268
Abstract: Following in the footsteps of the minimum information to report about a flow cytometry experiment (MIFlowCyt), an extracellular vesicle (EV) flow cytometry working group composed of members from the international societies of extracellular vesicles (ISEV),… read more here.
Keywords: vesicle flow; extracellular vesicle; reporting reliability; flow cytometry ... See more keywords
Extracellular vesicle long RNA markers of early‐stage lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34386
Abstract: Lung cancer screening by low‐dose computed tomography (LDCT) can improve mortality rates among high‐risk individuals, especially adenocarcinoma cases with characteristically poor prognosis, although high false‐positive rates have limited its clinical application. The objective of our… read more here.
Keywords: early stage; lung adenocarcinoma; extracellular vesicle; lung ... See more keywords
Label-free characterization of an extracellular vesicle-based therapeutic.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of extracellular vesicles"
DOI: 10.1002/jev2.12156
Abstract: Interest in mesenchymal stem cell derived extracellular vesicles (MSC-EVs) as therapeutic agents has dramatically increased over the last decade. Current approaches to the characterization and quality control of EV-based therapeutics include particle tracking techniques, Western… read more here.
Keywords: extracellular vesicle; vesicle based; free characterization; characterization extracellular ... See more keywords
Assessment of extracellular vesicle isolation methods from human stool supernatant
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12208
Abstract: Abstract Extracellular vesicles (EVs) are of growing interest due to their potential diagnostic, disease surveillance, and therapeutic applications. While several studies have evaluated EV isolation methods in various biofluids, there are few if any data… read more here.
Keywords: extracellular vesicle; stool supernatant; assessment extracellular; isolation ... See more keywords
Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12209
Abstract: Abstract Immune checkpoint inhibitor (ICI)‐based immunotherapy brought new hope for gastric cancer (GC) treatment. However, due to the lack of proper biomarkers, patient selection and outcome prediction for GC's immunotherapy remain unsatisfying. In this study,… read more here.
Keywords: predicting monitoring; extracellular vesicle; derived protein; immunotherapeutic outcomes ... See more keywords
Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12245
Abstract: Abstract Extracellular vesicles (EVs) are blood‐borne messengers that coordinate signalling between different tissues and organs in the body. The specificity of such crosstalk is determined by preferential EV docking to target sites, as mediated through… read more here.
Keywords: protein complexes; extracellular vesicles; extracellular vesicle; intact extracellular ... See more keywords
Understanding the extracellular vesicle surface for clinical molecular biology
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12260
Abstract: Abstract Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant roles in health and disease. EVs are abundant in body fluids and carry an array of molecules (proteins, lipids, nucleic acids and glycans) that… read more here.
Keywords: understanding extracellular; surface clinical; extracellular vesicle; surface ... See more keywords