Human fibroblast‐derived extracellular vesicles promote hair growth in cultured human hair follicles
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Letters"
DOI: 10.1002/1873-3468.14050
Abstract: Hair loss is a prevalent medical condition affecting both genders. In this study, we investigate the effects of a specific class of extracellular vesicles (EVs), namely human normal fibroblast‐derived EVs (hFB‐EVs), on human dermal papilla… read more here.
Keywords: extracellular vesicles; hfb evs; hair; fibroblast derived ... See more keywords
Extracellular vesicles and oncogenic signaling
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12855
Abstract: In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic markers for cancer therapy. While the field of EV research is rapidly developing and their application as vehicles for therapeutic cargo is being… read more here.
Keywords: extracellular vesicles; oncogenic signaling; signaling cascades; vesicles oncogenic ... See more keywords
Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13288
Abstract: The prognosis of metastatic urothelial carcinoma (mUC) patients is poor, and early prediction of systemic therapy response would be valuable to improve outcome. In this exploratory study, we investigated protein profiles in sequential plasma‐isolated extracellular… read more here.
Keywords: oncology; extracellular vesicles; metastatic urothelial; protein signatures ... See more keywords
Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13059
Abstract: Extracellular vesicles (EVs) contain various cargo molecules, including RNAs and proteins. EVs, which include exosomes, are predicted to be suitable surrogates of their source cells for liquid biopsy to measure biomarkers. Several studies have performed… read more here.
Keywords: extracellular vesicles; motor neurons; mrna content; motor ... See more keywords
Biogenic Supported Lipid Bilayers from Nanosized Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700200
Abstract: Fabrication of synthetic surfaces that reproduce structure and function of biological membranes is an open challenge. This work reports the first example of supported lipid bilayers obtained from extracellular vesicles (EVSLBs). EVSLBs harness and pattern… read more here.
Keywords: extracellular vesicles; nanosized extracellular; lipid bilayers; biogenic supported ... See more keywords
Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced functional materials"
DOI: 10.1002/adfm.202003237
Abstract: Tumor-derived extracellular vesicles (EVs) play essential roles in intercellular communication during tumor growth and metastatic evolution. Currently, little is known about the possible roles of tumor-derived EVs in sarcoma because the lack of specific surface… read more here.
Keywords: sarcoma; extracellular vesicles; chemistry; derived extracellular ... See more keywords
Physical Structuring of Injectable Polymeric Systems to Controllably Deliver Nanosized Extracellular Vesicles.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801604
Abstract: Extracellular vesicles (EVs) are emerging as a promising alternative approach to cell-therapies. However, to realize the potential of these nanoparticles as new regenerative tools, healthcare materials that address the current limitations of systemic administration need… read more here.
Keywords: extracellular vesicles; structuring injectable; polymeric systems; physical structuring ... See more keywords
Rapid Characterization and Quantification of Extracellular Vesicles by Fluorescence-Based Microfluidic Diffusion Sizing.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100021
Abstract: Extracellular vesicles (EVs) are emerging as promising diagnostic and therapeutic tools for a variety of diseases. The characterization of EVs requires a series of orthogonal techniques that are overall time- and material-consuming. Here, a microfluidic… read more here.
Keywords: extracellular vesicles; diffusion sizing; fluorescence; quantification ... See more keywords
Designer Extracellular Vesicles Modulate Pro‐Neuronal Cell Responses and Improve Intracranial Retention
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202100805
Abstract: Gene/oligonucleotide therapies have emerged as a promising strategy for the treatment of different neurological conditions. However, current methodologies for the delivery of neurogenic/neurotrophic cargo to brain and nerve tissue are fraught with caveats, including reliance… read more here.
Keywords: evs; pro neuronal; delivery; extracellular vesicles ... See more keywords
Harnessing the Natural Healing Power of Colostrum: Bovine Milk‐Derived Extracellular Vesicles from Colostrum Facilitating the Transition from Inflammation to Tissue Regeneration for Accelerating Cutaneous Wound Healing
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102027
Abstract: As wound healing is an extremely complicated process, consisting of a cascade of interlocking biological events, successful wound healing requires a multifaceted approach to support appropriate and rapid transitions from the inflammatory to proliferative and… read more here.
Keywords: colos evs; milk; facilitating transition; extracellular vesicles ... See more keywords
Engineered Delivery of Dental Stem‐Cell‐Derived Extracellular Vesicles for Periodontal Tissue Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102593
Abstract: Periodontal disease begins as an inflammatory response to a bacterial biofilm deposited around the teeth, which over time leads to the destruction of tooth‐supporting structures and consequently tooth loss. Conventional treatment strategies show limited efficacy… read more here.
Keywords: regeneration; extracellular vesicles; periodontal tissue; stem ... See more keywords