Human fibroblast‐derived extracellular vesicles promote hair growth in cultured human hair follicles
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Letters"
DOI: 10.1002/1873-3468.14050
Abstract: Hair loss is a prevalent medical condition affecting both genders. In this study, we investigate the effects of a specific class of extracellular vesicles (EVs), namely human normal fibroblast‐derived EVs (hFB‐EVs), on human dermal papilla… read more here.
Keywords: extracellular vesicles; hfb evs; hair; fibroblast derived ... See more keywords
Extracellular vesicles and oncogenic signaling
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12855
Abstract: In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic markers for cancer therapy. While the field of EV research is rapidly developing and their application as vehicles for therapeutic cargo is being… read more here.
Keywords: extracellular vesicles; oncogenic signaling; signaling cascades; vesicles oncogenic ... See more keywords
Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13288
Abstract: The prognosis of metastatic urothelial carcinoma (mUC) patients is poor, and early prediction of systemic therapy response would be valuable to improve outcome. In this exploratory study, we investigated protein profiles in sequential plasma‐isolated extracellular… read more here.
Keywords: oncology; extracellular vesicles; metastatic urothelial; protein signatures ... See more keywords
Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Oncology"
DOI: 10.1002/1878-0261.70086
Abstract: Early diagnosis of colorectal cancer (CRC) is crucial for successful treatment and mortality reduction. In this regard, blood‐based tests play an indispensable role. Current research is focused on molecules actively secreted by tumor cells into… read more here.
Keywords: colorectal cancer; extracellular vesicles; cancer; extensive validation ... See more keywords
Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13059
Abstract: Extracellular vesicles (EVs) contain various cargo molecules, including RNAs and proteins. EVs, which include exosomes, are predicted to be suitable surrogates of their source cells for liquid biopsy to measure biomarkers. Several studies have performed… read more here.
Keywords: extracellular vesicles; motor neurons; mrna content; motor ... See more keywords
Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70143
Abstract: The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to… read more here.
Keywords: extracellular vesicles; derived extracellular; cognitive resilience; resilience apolipoprotein ... See more keywords
Biogenic Supported Lipid Bilayers from Nanosized Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700200
Abstract: Fabrication of synthetic surfaces that reproduce structure and function of biological membranes is an open challenge. This work reports the first example of supported lipid bilayers obtained from extracellular vesicles (EVSLBs). EVSLBs harness and pattern… read more here.
Keywords: extracellular vesicles; nanosized extracellular; lipid bilayers; biogenic supported ... See more keywords
Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced functional materials"
DOI: 10.1002/adfm.202003237
Abstract: Tumor-derived extracellular vesicles (EVs) play essential roles in intercellular communication during tumor growth and metastatic evolution. Currently, little is known about the possible roles of tumor-derived EVs in sarcoma because the lack of specific surface… read more here.
Keywords: sarcoma; extracellular vesicles; chemistry; derived extracellular ... See more keywords
Extracellular Vesicles Functional “Brick‐Cement” Bio‐Integrated System for Annulus Fibrosus Repair
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202400066
Abstract: Due to the deficiency of mechanical supporting after discectomy and weak proliferative capacity of annulus fibrosus (AF) cells, the AF defect repair remains a clinical challenge. Herein, a myofibroblasts derived extracellular vesicles (M‐EVs) functional “brick‐cement”… read more here.
Keywords: extracellular vesicles; annulus fibrosus; bio; repair ... See more keywords
Noninvasive Assessment of Protease Activity in Osteosarcoma via Click Chemistry‐Mediated Enrichment of Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202422469
Abstract: Osteosarcoma (OS), the most common bone cancer in children, is characterized by aggressive tumors and subclinical metastasis. Metastasis significantly impacts OS patient survival rate, highlighting the need for frequent assessment of disease progression and treatment… read more here.
Keywords: extracellular vesicles; mmp; chemistry; disease progression ... See more keywords
Neutrophil Membrane‐Engineered Extracellular Vesicles from Perivascular Adipose Tissue‐Derived Stromal Cells for Atherosclerotic Lesion Resolution and Enhanced Vascular Graft Remodeling
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202503873
Abstract: Atherosclerosis is characterized by endothelial dysfunction and progressive plaque formation. Despite advancements in lipid‐lowering and anti‐inflammatory therapies, the repair of vascular damage and targeted delivery to atherosclerotic lesions remain critical challenges. Here, the development of… read more here.
Keywords: extracellular vesicles; neutrophil membrane; membrane engineered; engineered extracellular ... See more keywords