Global Extraction from Parallel Reaction Monitoring to Quantify Background Peptides for Improved Normalization and Quality Control in Targeted Proteomics.
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DOI: 10.1021/acs.analchem.1c01375
Abstract: Mass spectrometry-based targeted proteomics employs heavy isotope-labeled proteins or peptides as standards to improve accuracy and precision. The input sample amount is often determined by the total quantity of endogenous proteins or peptides, as defined… read more here.
Keywords: parallel reaction; reaction monitoring; targeted proteomics; global extraction ... See more keywords