Extragonadal germ cell tumors: Not just a matter of location. A review about clinical, molecular and pathological features
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DOI: 10.1002/cam4.2195
Abstract: Extragonadal germ cell tumors (EGGCTs) are uncommon neoplasms, which arise in anatomical locations other than gonads. The pathogenesis of these neoplasms is still poorly understood and it is a matter of debate if they really… read more here.
Keywords: cell tumors; extragonadal germ; germ cell; diagnosis ... See more keywords
Klinefelter syndrome and germ cell tumors: review of the literature
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DOI: 10.1186/s13633-020-00088-0
Abstract: Objective The most common presentation of Klinefelter syndrome (KS) is infertility and features of hypogonadism. Currently no consensus exists on the risk of malignancy in this syndrome. Several case reports show an incidence of extragonadal… read more here.
Keywords: klinefelter syndrome; cell; extragonadal germ; germ cell ... See more keywords
To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm
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DOI: 10.3390/ijms22115982
Abstract: In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency. Germ… read more here.
Keywords: cell extragonadal; cell tumor; extragonadal germ; germ cell ... See more keywords