Preoperative C‐reactive protein‐to‐albumin ratio predicts long‐term outcomes in extrahepatic cholangiocarcinoma patients
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DOI: 10.1002/jso.26175
Abstract: BACKGROUND Systemic inflammation may have prognostic value in some malignancies and association with lymph node metastasis. This study aimed to evaluate the impact of systemic inflammatory biomarkers on long-term and oncological outcomes as well as… read more here.
Keywords: extrahepatic cholangiocarcinoma; cholangiocarcinoma patients; node metastasis; cholangiocarcinoma ... See more keywords
Neoadjuvant therapy use and association with postoperative outcomes and overall survival in patients with extrahepatic cholangiocarcinoma
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DOI: 10.1002/jso.27112
Abstract: Evidence for neoadjuvant therapy (NAT) in extrahepatic cholangiocarcinoma (eCCA) is limited. Our objectives were to: (1) characterize treatment trends, (2) identify factors associated with receipt of NAT, and (3) evaluate associations between NAT and postoperative… read more here.
Keywords: postoperative outcomes; neoadjuvant therapy; therapy use; extrahepatic cholangiocarcinoma ... See more keywords
Prognostic Impact of Paraaortic Lymph Node Metastasis in Extrahepatic Cholangiocarcinoma
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DOI: 10.1007/s00268-020-05834-2
Abstract: Background Surgical resection in patients with extrahepatic cholangiocarcinoma (EHCC) with paraaortic lymph node metastasis (PALNM) remains controversial. The objective of this study was to investigate the prognostic impact of PALNM in resected EHCC. Methods The… read more here.
Keywords: paraaortic lymph; node metastasis; extrahepatic cholangiocarcinoma; prognostic impact ... See more keywords
Molecular Profiling and Treatment Pattern Differences between Intrahepatic and Extrahepatic Cholangiocarcinoma.
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DOI: 10.1093/jnci/djad046
Abstract: BACKGROUND Treatment patterns for intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC) differ, but limited studies exist comparing them. This study examines differences in molecular profiling rates and treatment patterns in these populations, focusing on use… read more here.
Keywords: treatment; molecular profiling; profiling treatment; extrahepatic cholangiocarcinoma ... See more keywords
Prolonged survival with first-line chemotherapy in advanced extrahepatic cholangiocarcinoma
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DOI: 10.1136/bcr-2022-249681
Abstract: Biliary tract cancer accounts for roughly 3% of adult malignancies of the gastrointestinal system. First-line treatment with gemcitabine–cisplatin chemotherapy is the standard for the management of metastatic biliary tract cancers. We present the case of… read more here.
Keywords: maintenance; first line; chemotherapy; extrahepatic cholangiocarcinoma ... See more keywords
ASO Author Reflections: Is Major Hepatopancreatoduodenectomy Beneficial for Patients with Advanced and Widespread Extrahepatic Cholangiocarcinoma?
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DOI: 10.1245/s10434-020-09261-4
Abstract: Major hepatopancreatoduodenectomy (HPD) is considered one of the few treatment options that can achieve negative resection margins for advanced or widespread extrahepatic cholangiocarcinoma. Despite reports on the short-term and long-term outcomes after major HPD from… read more here.
Keywords: extrahepatic cholangiocarcinoma; widespread extrahepatic; major hepatopancreatoduodenectomy; aso author ... See more keywords
Significance of dysplasia in bile duct resection margin in patients with extrahepatic cholangiocarcinoma: A retrospective analysis
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DOI: 10.12998/wjcc.v10.i10.3078
Abstract: BACKGROUND Radical resection is the only indicator associated with survival in extrahepatic cholangiocarcinoma (EHCC). However, limited data are available regarding the implications of dysplasia at the resection margin following surgery. AIM To evaluate the prognostic… read more here.
Keywords: margin; resection; resection margin; extrahepatic cholangiocarcinoma ... See more keywords
Endobiliary radiofrequency ablation for distal extrahepatic cholangiocarcinoma: A clinicopathological study
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DOI: 10.1371/journal.pone.0206694
Abstract: Background Most patients with distal extrahepatic cholangiocarcinoma have developed jaundice or cholangitis at the time of initial diagnosis, which can delay surgery. We aim to evaluate the actual EB-RFA ablation volume and validated the clinical… read more here.
Keywords: extrahepatic cholangiocarcinoma; ablation; endobiliary radiofrequency; distal extrahepatic ... See more keywords
Preoperative Bilirubin-Adjusted Carbohydrate Antigen 19-9 as a Prognostic Factor for Extrahepatic Cholangiocarcinoma Patients at a Single Center
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DOI: 10.2147/cmar.s229329
Abstract: Purpose The aims of our study were to investigate the prognostic impact of the rate of preoperative serum carbohydrate antigen 19-9/bilirubin (CA19-9/BR) on patients with extrahepatic bile duct cancer. Patients and Methods We collected clinical… read more here.
Keywords: prognostic factor; ca19 ratio; extrahepatic cholangiocarcinoma; carbohydrate antigen ... See more keywords
MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition
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DOI: 10.2147/ott.s170739
Abstract: Purpose To investigate the expression and functional role of Musashi2 (MSI2), an RNA-binding protein, in extrahepatic cholangiocarcinoma (eCCA). Patients and methods We measured MSI2 expression in human specimens and cell lines using Western blot and… read more here.
Keywords: extrahepatic cholangiocarcinoma; cell; invasion; ecca patients ... See more keywords
Establishment and validation of a prognostic nomogram for extrahepatic cholangiocarcinoma
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DOI: 10.3389/fonc.2022.1007538
Abstract: Simple summary Accurately estimate the prognosis of patients with ECCA is important. However, the TNM system has some limitations, such as low accuracy, exclusion of other factors (e.g., age and sex), and poor performance in… read more here.
Keywords: css; system; validation; risk ... See more keywords