Topical Combination of Fluorouracil and Calcipotriene as a Palliative Therapy for Refractory Extramammary Paget Disease
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.4793
Abstract: Importance Extramammary Paget disease (EMPD), a rare intraepithelial adenocarcinoma, poses a therapeutic challenge with high postoperative recurrence rates and a limited number of effective local treatment options. Objective To describe the use and efficacy of… read more here.
Keywords: combination; disease; fluorouracil; extramammary paget ... See more keywords
Assessment of the methods used to detect HER2-positive advanced extramammary Paget’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Medical Oncology"
DOI: 10.1007/s12032-018-1154-z
Abstract: The human epidermal growth factor receptor 2 (HER2) is recognized as an oncogene as well as a therapeutic target in various cancers. Certain patients with advanced extramammary Paget’s disease (EMPD) have also been reported to… read more here.
Keywords: her2 positive; empd; extramammary paget; advanced extramammary ... See more keywords
An advanced case of extramammary Paget disease: Safe and effective treatment in an inoperable elderly patient using extensive en face electron irradiation
Sign Up to like & getrecommendations! Published in 2019 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2018.08.010
Abstract: Extramammary Paget disease (EMPD) is an intraepithelial adenocarcinoma characterized by epithelial infiltration of large atypical cells with prominent nuclei.1 The disease process is hypothesized to originate in the apocrine sweat glands in the anogenital region.… read more here.
Keywords: disease; case; extramammary paget; electron ... See more keywords
Modified peripheral and central Mohs micrographic surgery for improved margin control in extramammary Paget disease
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DOI: 10.1016/j.jdcr.2020.11.002
Abstract: EMPD: extramammary Paget disease MMS: Mohs micrographic surgery WLE: wide local excision INTRODUCTION Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma of pluripotent keratinocyte stem cells, which typically occurs in elderly patients. The current… read more here.
Keywords: mohs micrographic; extramammary paget; margin control; micrographic surgery ... See more keywords
Efficacy of trastuzumab in HER-2-positive advanced extramammary Paget’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2022.2066472
Abstract: With strong interest, we read the review article, ‘Trastuzumab deruxtecan in HER-2-positive metastatic breast cancer and beyond’ by Perez et al. The authors summarize the characteristics and recent data regarding the efficacy and safety of… read more here.
Keywords: extramammary paget; empd; disease; therapy ... See more keywords
Intraoperative Immunostaining for Cytokeratin-7 During Mohs Micrographic Surgery Demonstrates Low Local Recurrence Rates in Extramammary Paget's Disease
Sign Up to like & getrecommendations! Published in 2018 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000001355
Abstract: BACKGROUND Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy with high recurrence rates following standard surgical treatments, ranging from 22% to 60% in large retrospective reviews. OBJECTIVE To evaluate the local recurrence rate of… read more here.
Keywords: surgery; recurrence; recurrence rates; extramammary paget ... See more keywords
Coexistence of condyloma acuminatum and extramammary Paget’s disease on penis and scrotum: A rare case report
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031754
Abstract: Rationale: Extramammary Paget’s disease (EMPD) is a rare skin cancer that commonly occurs in sites rich in apocrine glands, such as perineum, vulva, axilla, scrotum, and penis. On the other hand, condyloma acuminatum (CA; also… read more here.
Keywords: extramammary paget; scrotum; condyloma acuminatum; paget disease ... See more keywords
Five- and 10-year survival in extramammary Paget's disease: A focus on wide local excision.
Sign Up to like & getrecommendations! Published in 2023 at "Asia-Pacific journal of clinical oncology"
DOI: 10.1111/ajco.13964
Abstract: AIM This study aimed to analyze extramammary Paget's disease (EMPD)-specific survival, overall survival, and recurrence rate (RR) in patients with EMPD in South Korea, with a focus on wide local excision. METHODS We retrospectively reviewed… read more here.
Keywords: local excision; extramammary paget; disease; survival ... See more keywords
Extramammary Paget's disease of the perianal region: a 20‐year experience
Sign Up to like & getrecommendations! Published in 2017 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.12814
Abstract: To evaluate the results obtained from cases of perianal Paget's disease (PPD) and to provide a current perspective in the diagnostic evaluation and surgical management of this condition. read more here.
Keywords: disease perianal; extramammary paget; paget; paget disease ... See more keywords
Mechanisms of immune evasion in extramammary Paget disease
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15253
Abstract: restricted. Existing human leucocyte antigen (HLA) data is minimal in relation to anti-TB drugs. There has been an association reported in Korean patients with DRESS for the class I allele HLA-C*04:01, which extends to the… read more here.
Keywords: mechanisms immune; immune evasion; hla; extramammary paget ... See more keywords
Atypical cells on reflectance confocal microscopy may not represent melanoma: A case of axillary pigmented extramammary Paget disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13804
Abstract: Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently,… read more here.
Keywords: microscopy; histopathology; extramammary paget; pigmented extramammary ... See more keywords