Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation
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DOI: 10.1186/s12885-018-4467-6
Abstract: BackgroundRenal epithelioid angiomyolipomas (EAML) are rare tumors with aggressive behavior. EAML can be sporadic or develop within the tuberous sclerosis complex syndrome, where mutations of TSC1 or TSC2 genes (critical negative regulators of mTOR Complex… read more here.
Keywords: response; tsc2 mutation; case; sirolimus ... See more keywords