Extrapolating evidence for molecularly targeted therapies from common to rare cancers: a scoping review of methodological guidance
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-058350
Abstract: Objectives Cancer is increasingly classified according to biomarkers that drive tumour growth and therapies developed to target them. In rare biomarker-defined cancers, randomised controlled trials to adequately assess targeted therapies may be infeasible. Extrapolating existing… read more here.
Keywords: targeted therapies; extrapolating evidence; biomarker; extrapolation ... See more keywords