Articles with "extrapolation factors" as a keyword



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Use of a probabilistic PBPK/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos

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Published in 2017 at "Regulatory Toxicology and Pharmacology"

DOI: 10.1016/j.yrtph.2017.02.014

Abstract: &NA; A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model combined with Monte Carlo analysis of interā€individual variation was used to assess the effects of the insecticide, chlorpyrifos and its active metabolite, chlorpyrifos oxon in humans.… read more here.

Keywords: biochemistry; data derived; extrapolation factors; derived extrapolation ... See more keywords