Articles with "extrapolation ivive" as a keyword



AIVIVE: a novel AI framework for enhanced in vitro to in vivo extrapolation (IVIVE) of toxicogenomics data

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Published in 2025 at "Toxicological Sciences"

DOI: 10.1093/toxsci/kfaf100

Abstract: Abstract In vitro to in vivo extrapolation (IVIVE) of toxicogenomics (TGx) data is essential for enhancing mechanism-based toxicity evaluations and minimizing animal use. However, translating in vitro findings to in vivo responses remains challenging. Generative… read more here.

Keywords: novel framework; vivo; extrapolation ivive; vitro vivo ... See more keywords