Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules
Sign Up to like & getrecommendations! Published in 2022 at "EJNMMI Research"
DOI: 10.1186/s13550-022-00893-z
Abstract: Background Extrapolation of human absorbed doses (ADs) from biodistribution experiments on laboratory animals is used to predict the efficacy and toxicity profiles of new radiopharmaceuticals. Comparative studies between available animal-to-human dosimetry extrapolation methods are missing.… read more here.
Keywords: extrapolation; organ specific; extrapolation methods; nodaga rgdyk ... See more keywords