The Number of Circulating Fetal Extravillous Trophoblasts Varies from Gestational Week 6 to 20
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DOI: 10.1007/s43032-020-00243-1
Abstract: Cell-based non-invasive prenatal testing (cbNIPT) based on circulating fetal extravillous trophoblasts (fEVTs) has shown to be possible in gestational week (GW) 10–13. Prenatal testing is relevant for a wider time period than GW 10–13, but… read more here.
Keywords: extravillous trophoblasts; number circulating; fetal extravillous; number ... See more keywords
Transforming growth factor-β signaling governs the differentiation program of extravillous trophoblasts in the developing human placenta
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2120667119
Abstract: Significance During pregnancy, extravillous trophoblasts (EVTs) detach from anchoring sites of the placenta, differentiate, and invade the maternal uterus to remodel its vasculature. Failures in this program contribute to placentation defects observed in gestational disorders… read more here.
Keywords: extravillous trophoblasts; transforming growth; growth; program ... See more keywords
Human Extravillous Trophoblasts Penetrate Decidual Veins and Lymphatics before Remodeling Spiral Arteries during Early Pregnancy
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DOI: 10.1371/journal.pone.0169849
Abstract: In humans, the defective invasion of the maternal endometrium by fetal extravillous trophoblasts (EVTs) can lead to insufficient perfusion of the placenta, resulting in pregnancy complications that can put both mother and baby at risk.… read more here.
Keywords: pregnancy; human extravillous; extravillous trophoblasts; veins lymphatics ... See more keywords
The effect of maternal NODAL on STOX1 expression in extravillous trophoblasts is mediated by IGF1
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DOI: 10.1371/journal.pone.0202190
Abstract: The number of molecules identified to be involved in communication between placenta and decidua is fast expanding. Previously, we showed that NODAL expressed in maternal endometrial stromal cells is able to affect NODAL and STOX1… read more here.
Keywords: extravillous trophoblasts; igf1; effect; expression ... See more keywords