Amyloidosis increase is not attenuated by long-term calorie restriction or related to neuron density in the prefrontal cortex of extremely aged rhesus macaques.
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DOI: 10.1007/s11357-020-00259-0
Abstract: As human lifespan increases and the population ages, diseases of aging such as Alzheimer's disease (AD) are a major cause for concern. Although calorie restriction (CR) as an intervention has been shown to increase healthspan… read more here.
Keywords: calorie restriction; rhesus; increase; density ... See more keywords
Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats
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DOI: 10.3390/ijms20102601
Abstract: While mitochondrial dysfunction is acknowledged as a major feature of aging, much less is known about the role of mitochondria in extended longevity. Livers from aged (28-month-old) and extremely aged (32-month-old) rats were analyzed for… read more here.
Keywords: month old; mtdna; old rats; tfam binding ... See more keywords