Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesis
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DOI: 10.7150/jca.79905
Abstract: Eyes absent homologue 4 (EYA4) is silenced in pancreatic ductal adenocarcinoma (PDAC) and functions as a tumor suppressor to restrain PDAC development, albeit the molecular mechanism underlying its downregulation remains enigmatic. Methods: Functional studies were… read more here.
Keywords: motif containing; tripartite motif; eya4; pancreatic tumorigenesis ... See more keywords