Development and validation of Ketorolac Tromethamine in eye drop formulation by RP-HPLC method
Sign Up to like & getrecommendations! Published in 2017 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2012.12.031
Abstract: Abstract A simple, precise and accurate method was developed and validated for analysis of Ketorolac Tromethamine in eye drop formulation. An isocratic HPLC analysis was performed on Kromosil C18 column (150 cm × 4.6 mm × 5 μm). The compound was separated… read more here.
Keywords: drop formulation; method; eye drop; tromethamine eye ... See more keywords
Ocular tissue distribution and pharmacokinetic study of a small 13kDa domain antibody after intravitreal, subconjuctival and eye drop administration in rabbits.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental eye research"
DOI: 10.1016/j.exer.2017.10.021
Abstract: Domain antibodies (dAb's) comprise the smallest functional unit of human IgG and can be targeted to a range of different soluble cytokine and receptor targets in the eye. In particular their small size may offer… read more here.
Keywords: eye drop; ocular tissue; eye; domain ... See more keywords
Novel approaches for improving stability of cysteamine formulations
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.08.006
Abstract: Graphical abstract Figure. No Caption available. Abstract Cystinosis is a genetic disorder that leads to the formation of cystine crystals in many organs in the body including cornea. Ocular manifestation of this disease is treated… read more here.
Keywords: drop bottle; cysteamine; eye drop; stability ... See more keywords
Monocaprin eye drop formulation to combat antibiotic resistant gonococcal blindness
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DOI: 10.1038/s41598-020-68722-8
Abstract: Neisseria gonorrhoeae bacteria are acknowledged as an urgent threat to human health because this species has developed resistances to all of the antibiotics used clinically to treat its infections. N. gonorrhoeae causes the sexually transmitted… read more here.
Keywords: monocaprin; drop formulation; eye drop; formulation combat ... See more keywords
Validation of a More Reliable Method of Eye Drop Self-Administration.
Sign Up to like & getrecommendations! Published in 2020 at "Optometry and Vision Science"
DOI: 10.1097/opx.0000000000001535
Abstract: SIGNIFICANCE We propose an alternative method for eye drop self-administration. Similar IOP reductions were found with this method compared with clinician instillation. The alternative method of self-administration potentially benefits patients who have trouble successfully instilling… read more here.
Keywords: administration; drop; instillation; method ... See more keywords
Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop
Sign Up to like & getrecommendations! Published in 2022 at "Acta Ophthalmologica"
DOI: 10.1111/aos.15163
Abstract: To investigate the effect of polyquaternium‐1 (PQ)‐preserved and benzalkonium chloride (BAK)‐preserved travoprost eye drops on viability of primary human conjunctival goblet cell (GC) cultures and on secretion of mucin and cytokines. Furthermore, to evaluate the… read more here.
Keywords: preserved travoprost; benzalkonium chloride; travoprost eye; eye drops ... See more keywords
Hemodynamic Changes Associated with Mydriatic Eye Drop Administration in Anesthetized Pediatric Patients
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DOI: 10.1159/000500593
Abstract: Background: Dilating eye drops are routinely used in pediatric retinoblastoma patients during anesthetized ophthalmologic exams. Information on the systemic effects of ocular mydriatics, especially in anesthetized pediatric patients, is limited. Objective: The primary aim of… read more here.
Keywords: administration; eye drop; drop administration; pediatric patients ... See more keywords
The Effects of 3% Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostics"
DOI: 10.3390/diagnostics10010020
Abstract: Anti-glaucoma eye drop treatment often induces dry eyes and can lead to poor medication adherence. This study aimed to investigate the effects of 3% diquafosol sodium eye drops on tear function and the ocular surface… read more here.
Keywords: eye drops; group; eye drop; anti glaucoma ... See more keywords
Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop Formulation
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DOI: 10.3390/ma12020229
Abstract: The topical administration route is commonly used for targeting therapeutics to the eye; however, improving the bioavailability of drugs applied directly to the eye remains a challenge. Different strategies have been studied to address this… read more here.
Keywords: drop formulation; formulation; eye drop; spectroscopy ... See more keywords
Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics10040208
Abstract: Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water solubility. Solid… read more here.
Keywords: drop formulation; micelle; water; eye drop ... See more keywords
Formulation and Stability of Ataluren Eye Drop Oily Solution for Aniridia
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DOI: 10.3390/pharmaceutics13010007
Abstract: Congenital aniridia is a rare and severe panocular disease characterized by a complete or partial iris defect clinically detectable at birth. The most common form of aniridia occurring in around 90% of cases is caused… read more here.
Keywords: stability ataluren; formulation; eye drop; ataluren eye ... See more keywords