A Bioequivalence Study With Pharmacokinetic Endpoints for Azithromycin Eye Drops.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1226
Abstract: Azithromycin eye drops with a bioadhesive ocular drug-delivery system can offer a simplified dosing regimen. In this study, we compared the pharmacokinetic properties and assessed the bioequivalence of a newly developed generic azithromycin eye drop… read more here.
Keywords: bioequivalence; azithromycin eye; bioequivalence study; eye drops ... See more keywords
Factors influencing the outcomes of trabeculectomy, conventional canaloplasty, and mitomycin C augmented canaloplasty
Sign Up to like & getrecommendations! Published in 2024 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-024-06656-x
Abstract: To compare the efficacy, safety, and factors influencing the outcomes of trabeculectomy (TE), conventional canaloplasty (cCP), and mitomycin C augmented canaloplasty (mCP) in glaucoma patients. Intraocular pressure (IOP), the number of IOP-lowering eye drops, and… read more here.
Keywords: ccp mcp; iop; iop lowering; lowering eye ... See more keywords
Alleviation of dry eye syndrome with one dose of antioxidant, anti-inflammatory, and mucoadhesive lysine-carbonized nanogels.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.01.044
Abstract: Most dry eye syndromes (DES) are caused by oxidative stress and an overactive inflammatory response, leading to tear deficiency and excessive tear evaporation. Conventional eye drops for DES treatment require high doses and frequent administration… read more here.
Keywords: dry eye; eye; lys cngs; dose ... See more keywords
Influence of artificial tears on keratometric measurements in cataract patients.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2020.08.024
Abstract: PURPOSE Assessing the influence of artificial tears of different viscosity on K-readings prior to cataract surgery. DESIGN Prospective randomized cross-over, before-and-after clinical study METHODS: Setting: Department of Ophthalmology, Medical University Vienna PATIENT POPULATION: A total… read more here.
Keywords: dry eyes; influence artificial; viscosity; eye drops ... See more keywords
Hydrogel eye drops as a non-invasive drug carrier for topical enhanced Adalimumab permeation and highly efficient uveitis treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.117216
Abstract: Uveitis is one of the most popular blind-causing eye diseases worldwide. Adalimumab (ADA) is used for the uveitis treatment through systemic or intravitreal injection at the expense of systemic side effects and increased medical risks.… read more here.
Keywords: permeation; treatment; eye drops; non invasive ... See more keywords
Antioxidant and anti-glycated TAT-modified platinum nanoclusters as eye drops for non-invasive and painless relief of diabetic cataract in rats
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.125436
Abstract: Abstract Diabetic cataract (DC) is a kind of worrying ocular complications that eventually leads to blindness. However, there are a narrow range of pharmacological interventions to enable control the progression of DC, especially the eye… read more here.
Keywords: eye drops; non invasive; invasive painless; diabetic cataract ... See more keywords
Better Persistence Rates with Mirabegron: Questions Raised.
Sign Up to like & getrecommendations! Published in 2017 at "European urology"
DOI: 10.1016/j.eururo.2017.03.040
Abstract: In this issue of European Urology, Chapple et al [1] report on persistence rates and median time to discontinuation for a number of drugs routinely prescribed for overactive bladder (OAB). The report raises some important… read more here.
Keywords: persistence rates; eye drops; rates mirabegron; urology ... See more keywords
pH measurement and phosphate determination in pharmaceutical eye drops for eye diseases by digital image analysis
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.105854
Abstract: Abstract A method based on Digital Image Analysis (DIA) is described to quantify pH and phosphates simultaneously in eye drops for the treatment of glaucoma and dry eye syndrome. In this work, images acquired with… read more here.
Keywords: eye drops; phosphate determination; digital image; image analysis ... See more keywords
Hyperosmolar eye drops for diurnal corneal edema in Fuchs' endothelial dystrophy: a double-blind randomized-controlled trial.
Sign Up to like & getrecommendations! Published in 2021 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2021.04.015
Abstract: PURPOSE The Eye Drops for Early Morning-Associated Swelling (EDEMAS) trial assessed the efficacy of hyperosmolar eye drops on corneal edema resolution. DESIGN Double-blind randomized-controlled trial of hyperosmolar eye drops vs. placebo. PARTICIPANTS Participants with Fuchs'… read more here.
Keywords: corneal; treatment; eye drops; edema ... See more keywords
A case of drug induced lung injury caused by levofloxacin eye drops
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2018.03.010
Abstract: A 78 year-old man, who received levofloxacin eye drops as a perioperative prophylactic antibacterial agent for cataract surgery, developed pyrexia and dyspnea, followed by respiratory failure. He was diagnosed as drug-induced lung injury due to… read more here.
Keywords: lung injury; levofloxacin eye; induced lung; eye drops ... See more keywords
In Situ Gelling Eye Drops of Tacrolimus with Improved Ocular Delivery and Therapeutic Efficacy.
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c01259
Abstract: In situ gelling eye drops of tacrolimus (FK506 Gel) were developed to address the formulation challenge of tacrolimus for anterior ocular inflammatory diseases. Both in silico and in vitro investigations were conducted to screen a… read more here.
Keywords: drops tacrolimus; situ gelling; eye drops; fk506 gel ... See more keywords