An alternative predictor of eye irritation that utilizes potential parameters of the human corneal epithelium model calculated based on Hansen solubility parameters.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.01.019
Abstract: Eye irritation predictions are very important in the development of cosmetics and pharmaceuticals. For animal protection, alternative tests are being developed to replace the Draize test, which involves the use of rabbits to test eye… read more here.
Keywords: eye irritation; vitrigel eit; hansen solubility; eye ... See more keywords
A retrospective analysis of in vivo eye irritation, skin irritation and skin sensitisation studies with agrochemical formulations: Setting the scene for development of alternative strategies
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.06.014
Abstract: &NA; Analysis of the prevalence of health effects in large scale databases is key in defining testing strategies within the context of Integrated Approaches on Testing and Assessment (IATA), and is relevant to drive policy… read more here.
Keywords: irritation skin; eye irritation; agrochemical formulations; analysis ... See more keywords