Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila
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DOI: 10.1371/journal.pone.0187546
Abstract: A limited collection of signaling networks and transcriptional effectors directs the full spectrum of cellular behaviors that comprise development. One mechanism to diversify regulatory potential is to combine multiple biochemical activities into the same protein.… read more here.
Keywords: determination gene; phosphatase; tyrosine phosphatase; eyes absent ... See more keywords
The Eyes Absent Proteins: Unusual HAD Family Tyrosine Phosphatases
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DOI: 10.3390/ijms22083925
Abstract: Here, we review the haloacid dehalogenase (HAD) class of protein phosphatases, with a particular emphasis on an unusual group of enzymes, the eyes absent (EYA) family. EYA proteins have the unique distinction of being structurally… read more here.
Keywords: eya proteins; tyrosine phosphatases; family tyrosine; eya family ... See more keywords