The functions of EZH2 in immune cells: Principles for novel immunotherapies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1ru0520-311r
Abstract: Enhancer of zeste homolog 2 (EZH2) is aberrantly expressed or mutated in multiple types of cancer cells and plays an oncogenic role in tumorigenesis and development in most cancers. Results from pilot clinical studies have… read more here.
Keywords: roles ezh2; cancer cells; functions ezh2; cancer ... See more keywords
Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia.
Sign Up to like & getrecommendations! Published in 2019 at "Blood advances"
DOI: 10.1182/bloodadvances.2018030262
Abstract: Microenvironmental stimuli affect EZH2 expression and function in CLL. Combined B-cell signaling and EZH2 inhibition showed synergistic effects on primary CLL cells. read more here.
Keywords: exerts synergistic; ezh2 immune; inhibition; immune signaling ... See more keywords