Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 Genes
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DOI: 10.2147/jir.s374951
Abstract: Background In most cell types, replicative senescence (RS) is supposed to be a principle causative factor for aging. Atrial fibrosis, pathologically characterized by proliferation of atrial fibroblasts (AFs) and excessive accumulation of extracellular matrix proteins,… read more here.
Keywords: ezh2 inhibits; promoter regions; replicative senescence; atrial fibroblasts ... See more keywords