Betulinic acid purified from Alstonia boonei inhibits folate biosynthesis in malarial Plasmodium, enhances mitochondrial pore opening and F1F0 ATPase in mice
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DOI: 10.1016/j.molstruc.2021.130454
Abstract: Abstract Activity-guided assay of antimalarial properties of Alstonia boonei led to the purification of betulinic acid from the chloroform fraction of the methanol stem bark extract. The structure and stereochemistry of betulinic acid from A.… read more here.
Keywords: betulinic acid; alstonia boonei; acid; f1f0 atpase ... See more keywords
Streptococcus salivarius Isolates of Varying Acid Tolerance Exhibit F1F0-ATPase Conservation
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DOI: 10.1159/000516175
Abstract: Genes encoding the subunits of the membrane-bound F1F0-ATPase (responsible for exporting protons from the cytoplasm and contributing to acid tolerance) were sequenced for 24 non-mutans streptococci isolated from carious lesions. Isolates, mostly Streptococcus salivarius, displayed… read more here.
Keywords: streptococcus salivarius; tolerance; f1f0 atpase; acid tolerance ... See more keywords